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Table 2 Acne lesion counts in subjects after treatment with EE/CMA or EE/DRSP

From: A comparison of combined oral contraceptives containing chlormadinone acetate versus drospirenone for the treatment of acne and dysmenorrhea: a randomized trial

Testing for Efficacy

EE/CMAa (n = 90)

EE/DRSPa (n = 90)

Baseline

Month 1

Month 3

Month 6

Baseline

Month 1

Month 3

Month 6

Mean ± S.D.

Mean change from baseline ± S.D.

Mean ± S.D.

Mean change from baseline ± S.D.

Acne

 Comedones

47.17 ± 22.30

−9.21 ± 1.22

− 23.37 ± 1.67

− 35.00 ± 1.95

42.94 ± 21.08

− 7.02 ± 1.22

− 19.33 ± 1.67

− 28.82 ± 1.95

 Papules

14.60 ± 6.63

− 3.34 ± 0.48

−6.29 ± 0.57

− 9.74 ± 0.63

13.67 ± 5.94

−2.16 ± 0.48

−5.06 ± 0.57

−7.57 ± 0.63

 Pustules/Nodules

3.1 ± 3.59

−0.23 ± 0.35

−1.55 ± 0.40

−2.38 ± 0.47

3.14 ± 4.29

−0.6 ± 0.35

−2.02 ± 0.397

−2.43 ± 0.47

   Total Lesions

64.21 ± 25.09

−12.40 ± 1.35

−30.84 ± 1.75

− 46.78 ± 2.11

59.66 ± 23.44

−9.47 ± 1.35

−26.52 ± 1.75

−38.90 ± 2.11

  1. aContinuous variables are presented as mean ± S.D. Counts show changes month by month within treatment groups