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Table 3 Lifetime incidence of side effects of HC in all participants (total) and comparing participants with a psychiatric history and those without psychiatric history. P values represent a comparison of means between the two groups (separated based on psychiatric history) using a t-test

From: Psychological side effects of hormonal contraception: a disconnect between patients and providers

Side Effect

Total ( N  = 188)

No Psychiatric History ( N  = 98)

Psychiatric History ( N  = 80)

P value

n (%)

n (%)

n (%)

Mood Changes

82 (43.6)

29 (29.5)

49 (61.2)

0.000016*

Irregular Bleeding

72 (38.3)

41(41.8)

27 (33.8)

0.272

Weight Gain

64 (34.0)

27 (27.6)

34 (42.5)

0.229

Cramps/Pain

47 (25.0)

22 (22.4)

22 (27.5)

0.440

Loss of Libido/Sexual Satisfaction

42 (22.3)

21 (21.4)

19 (23.8)

0.714

Acne

38 (20.2)

18 (18.4)

18 (22.5)

0.497

No Side Effects

38 (20.2)

23 (23.4)

13 (16.3)

0.235

Headaches

10 (5.3)

3 (3.1)

7 (8.8)

0.102

Nausea

5 (2.7)

1 (1.0)

4 (5.0)

0.111

Heavy Bleeding

3 (1.6)

2 (2.5)

0

0.117

Clots

2 (1.1)

1 (1.0)

1 (1.3)

0.886

Other

28 (14.9)

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